Obesity, weight loss and prognosis in type 2 diabetes. Diabet Franks S. Polycystic ovary syndrome. Evaluation and therapy of polycystic ovarian syndrome. How to Lose Weight Even If You Have PCOS: 8 Science-Backed Tips. PCOS (polycystic ovary syndrome) is a common hormonal disorder that affects up to 20%. Polycystic Ovary Syndrome (PCOS) is one of the common endocrine diseases Therefore, the weight loss prior to conception improves live birth rate in obese.
Revista: Current Pharmaceutical Design. Idioma: Inglés. Tipo de recurso: Artículo publicado. PCOS has diverse clinical implications that include reproductive infertility, hyperandrogenism, hirsutismmetabolic insulin resistance, impaired glucose tolerance, type 2 diabetes mellitus, cardiovascular diseases and psychological features increased anxiety, depression and worsened quality of life. The exact patho-physiology of PCOS is complex and remains largely unclear.
The phenotype varies widely depending on life stage, genotype, ethnicity and environmental factors including lifestyle and body weight. During the last decades, obesity and excess weight are major chronic diseases all around the word.
Obesity increases some features of PCOS such as hyperandrogenism, hirsutism, infertility and pregnancy complications. Both obesity and insulin resistance increase diabetes mellitus type 2 and cardiovascular diseases. Moreover, obesity impairs insulin resistance and exacerbates reproductive and metabolic features of PCOS. It is well known that obesity is associated with anovulation, pregnancy loss and late pregnancy complications pre-eclampsia, gestational diabetes.
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